2. Gene
  3. Ubr4 - ubiquitin protein ligase E3 component n-recognin 4 Gene

Ubr4 - ubiquitin protein ligase E3 component n-recognin 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p600; Zubr1; Gm1032; Gm1666; RBAF600; mKIAA0462; 1810009A16Rik; A930005E13Rik; D930005K06Rik

基因 ID: 69116 | 基因类型: protein coding

关于 Ubr4

功能概要

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including cytoplasm; cytoskeleton; and nucleus. Predicted to be integral component of membrane. Predicted to be active in centrosome; cytosol; and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human UBR4 (ubiquitin protein Ligase E3 component n-recognin 4). [provided by Alliance of Genome Resources, Apr 2022]

Ubr4 基因产物(1)

mRNA Protein Name
NM_001160319.1 NP_001153791.1 E3 ubiquitin-protein ligase UBR4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calmodulin binding IDA
IDA: 通过直接分析推断
30111582 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16081543 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
19008229 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endosome organization IDA
IDA: 通过直接分析推断
30111582 MGI
involved in positive regulation of autophagy IMP
IMP: 通过突变表型推断
23431188 MGI
acts upstream of or within protein catabolic process IMP
IMP: 通过突变表型推断
37871017 MGI
acts upstream of or within protein stabilization IMP
IMP: 通过突变表型推断
37871017 MGI
involved in ubiquitin-dependent protein catabolic process via the N-end rule pathway IDA
IDA: 通过直接分析推断
16055722 MGI
involved in ubiquitin-dependent protein catabolic process via the N-end rule pathway IMP
IMP: 通过突变表型推断
23431188 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
30111582 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase UBR4

N-recognin-4

RING-type E3 ubiquitin transferase UBR4

retinoblastoma-associated factor 600

zinc finger UBR1-type protein 1

zinc finger, UBR1 type 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS19394 Ubr4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15389 UBR4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25886 Ubr4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ubr4 NCBI NCBI:23352
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