2. Gene
  3. Degs2 - delta(4)-desaturase, sphingolipid 2 Gene

Degs2 - delta(4)-desaturase, sphingolipid 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DES2; 2210008A03Rik

基因 ID: 70059 | 基因类型: protein coding

关于 Degs2

功能概要

Enables sphingolipid delta-4 desaturase activity and sphingosine hydroxylase activity. Acts upstream of or within ceramide biosynthetic process and sphinganine metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in stomach. Orthologous to human DEGS2 (delta 4-desaturase, sphingolipid 2). [provided by Alliance of Genome Resources, Apr 2022]

Degs2 基因产物(2)

mRNA Protein Name
NM_001171002.1 NP_001164473.1 sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform 2
NM_027299.5 NP_081575.2 sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sphingolipid delta-4 desaturase activity IGI
IGI: 通过遗传相互作用推断
11937514 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within sphinganine metabolic process IGI
IGI: 通过遗传相互作用推断
11937514 MGI
acts upstream of or within sphingolipid biosynthetic process IGI
IGI: 通过遗传相互作用推断
11937514 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

degenerative spermatocyte homolog 2, lipid desaturase

sphingolipid 4-desaturase

sphingolipid C4-monooxygenase

sphingolipid delta 4 desaturase/C-4 hydroxylase

sphingolipid delta(4)-desaturase/C4-hydroxylase DES2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03683 DEGS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-161804 GNF-2-deg Degrader / 否
HY-RS20908 Degs2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27425 Degs2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Degs2 NCBI NCBI:123099
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