2. Gene
  3. Pank2 - pantothenate kinase 2 Gene

Pank2 - pantothenate kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: hPanK2; 4933409I19Rik

基因 ID: 74450 | 基因类型: protein coding

关于 Pank2

功能概要

Enables pantothenate kinase activity. Acts upstream of or within several processes, including coenzyme A biosynthetic process; mitochondrion morphogenesis; and spermatid development. Located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in pantothenate kinase-associated neurodegeneration. Orthologous to human PANK2 (pantothenate kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Pank2 基因产物(10)

mRNA Protein Name
NM_001355679.1 NP_001342608.1 pantothenate kinase 2, mitochondrial isoform b
NM_001355681.1 NP_001342610.1 pantothenate kinase 2, mitochondrial isoform c
NM_001355682.1 NP_001342611.1 pantothenate kinase 2, mitochondrial isoform c
NM_001355683.1 NP_001342612.1 pantothenate kinase 2, mitochondrial isoform d
NM_153501.3 NP_705721.3 pantothenate kinase 2, mitochondrial isoform a
NM_001355679.1 NP_001342608.1 pantothenate kinase 2, mitochondrial isoform b
NM_001355681.1 NP_001342610.1 pantothenate kinase 2, mitochondrial isoform c
NM_001355682.1 NP_001342611.1 pantothenate kinase 2, mitochondrial isoform c
NM_001355683.1 NP_001342612.1 pantothenate kinase 2, mitochondrial isoform d
NM_153501.3 NP_705721.3 pantothenate kinase 2, mitochondrial isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables pantothenate kinase activity IDA
IDA: 通过直接分析推断
17825826 MGI
enables pantothenate kinase activity IGI
IGI: 通过遗传相互作用推断
11479594 MGI
enables pantothenate kinase activity IMP
IMP: 通过突变表型推断
17379144 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aerobic respiration IMP
IMP: 通过突变表型推断
22983956 MGI
involved in coenzyme A biosynthetic process IGI
IGI: 通过遗传相互作用推断
22815849 MGI
acts upstream of or within coenzyme A biosynthetic process IMP
IMP: 通过突变表型推断
22815849 MGI
involved in coenzyme A biosynthetic process IMP
IMP: 通过突变表型推断
24316510 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
22983956 MGI
acts upstream of or within regulation of mitochondrial membrane potential IMP
IMP: 通过突变表型推断
22983956 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
15525657 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
17825826 MGI
is active in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
22983956 MGI
NOT located in mitochondrion IDA
IDA: 通过直接分析推断
17825826 MGI
located in mitochondrion IMP
IMP: 通过突变表型推断
22983956 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pantothenate kinase 2, mitochondrial

pantothenate kinase 2 (Hallervorden-Spatz syndrome)

pantothenic acid kinase 2

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-44170 Pantothenate kinase-IN-2 Inhibitor 98.18% 否
HY-159509 Claziprotamidum Modulator / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pank2 NCBI NCBI:80025
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