2. Gene
  3. Abhd12 - abhydrolase domain containing 12 Gene

Abhd12 - abhydrolase domain containing 12 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1500011G07Rik; 6330583M11Rik

基因 ID: 76192 | 基因类型: protein coding

关于 Abhd12

功能概要

Enables acylglycerol Lipase activity; lysophospholipase activity; and palmitoyl-(protein) hydrolase activity. Involved in cellular lipid catabolic process; protein depalmitoylation; and regulation of inflammatory response. Acts upstream of or within adult walking behavior; phosphatidylserine catabolic process; and response to auditory stimulus. Located in dendrite cytoplasm and endoplasmic reticulum membrane. Is integral component of membrane. Part of AMPA glutamate receptor complex. Used to study PHARC syndrome. Human ortholog(s) of this gene implicated in PHARC syndrome. Orthologous to human ABHD12 (abhydrolase domain containing 12, lysophospholipase). [provided by Alliance of Genome Resources, Apr 2022]

Abhd12 基因产物(3)

mRNA Protein Name
NM_001356549.1 NP_001343478.1 lysophosphatidylserine lipase ABHD12 isoform 2
NM_001356550.1 NP_001343479.1 lysophosphatidylserine lipase ABHD12 isoform 3
NM_024465.3 NP_077785.2 lysophosphatidylserine lipase ABHD12 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lysophospholipase activity IDA
IDA: 通过直接分析推断
30237167 MGI
enables lysophospholipase activity IMP
IMP: 通过突变表型推断
25580854 MGI
enables monoacylglycerol lipase activity IDA
IDA: 通过直接分析推断
18096503 MGI
enables palmitoyl-(protein) hydrolase activity IDA
IDA: 通过直接分析推断
27307232 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acylglycerol catabolic process IDA
IDA: 通过直接分析推断
18096503 MGI
acts upstream of or within adult walking behavior IMP
IMP: 通过突变表型推断
23297193 MGI
involved in monoacylglycerol catabolic process IDA
IDA: 通过直接分析推断
30237167 MGI
acts upstream of or within phosphatidylserine catabolic process IMP
IMP: 通过突变表型推断
23297193 MGI
involved in phospholipid catabolic process IDA
IDA: 通过直接分析推断
30237167 MGI
involved in phospholipid catabolic process IMP
IMP: 通过突变表型推断
25580854 MGI
involved in protein depalmitoylation IDA
IDA: 通过直接分析推断
27307232 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
30643283 MGI
acts upstream of or within response to auditory stimulus IMP
IMP: 通过突变表型推断
23297193 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
22632720 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
27307232 MGI
located in dendrite cytoplasm IDA
IDA: 通过直接分析推断
27307232 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
30237167 MGI
located in membrane IDA
IDA: 通过直接分析推断
18096503 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysophosphatidylserine lipase ABHD12

2-arachidonoylglycerol hydrolase ABHD12

abhydrolase domain-containing protein 12

monoacylglycerol lipase ABHD12

oxidized phosphatidylserine lipase ABHD12

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114157 DO-264 Inhibitor 99.96% 否
HY-139174 (S)-DO271 / 否
HY-152152 JZP-MA-13 Inhibitor / 否
HY-RS00086 ABHD12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00087 ABHD12B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21811 Abhd12 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28327 Abhd12 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abhd12 NCBI NCBI:26090
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