2. Gene
  3. Polq - polymerase (DNA directed), theta Gene

Polq - polymerase (DNA directed), theta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: A430110D14Rik

基因 ID: 77782 | 基因类型: protein coding

关于 Polq

功能概要

Enables DNA-directed DNA Polymerase activity. Involved in double-strand break repair via alternative nonhomologous end joining; negative regulation of double-strand break repair via homologous recombination; and somatic hypermutation of immunoglobulin genes. Acts upstream of or within DNA repair. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Is expressed in embryo; heart; spleen; and testis. Orthologous to human POLQ (DNA Polymerase theta). [provided by Alliance of Genome Resources, Apr 2022]

Polq 基因产物(2)

mRNA Protein Name
NM_001159369.1 NP_001152841.1 DNA polymerase theta isoform 2
NM_029977.2 NP_084253.1 DNA polymerase theta isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA helicase activity IDA
IDA: 通过直接分析推断
29058711 MGI
enables DNA-directed DNA polymerase activity IDA
IDA: 通过直接分析推断
29058711 MGI
enables DNA-directed DNA polymerase activity IMP
IMP: 通过突变表型推断
25642960 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA repair IGI
IGI: 通过遗传相互作用推断
15542845 MGI
acts upstream of or within DNA repair IMP
IMP: 通过突变表型推断
12663541 MGI
involved in double-strand break repair via alternative nonhomologous end joining IDA
IDA: 通过直接分析推断
25642960 MGI
involved in negative regulation of double-strand break repair via homologous recombination IDA
IDA: 通过直接分析推断
25642960 MGI
involved in negative regulation of double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
28687761 MGI
involved in somatic hypermutation of immunoglobulin genes IMP
IMP: 通过突变表型推断
16172387 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA polymerase theta

DNA polymerase eta

chromosome aberrations occurring spontaneously protein 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10836 POLQ Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-182322 POLQ-IN-1 Inhibitor / 否
HY-RS10833 POLK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17891 Polq Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24360 Polq Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Polq NCBI NCBI:10721
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