2. Gene
  3. PARP8 - poly(ADP-ribose) polymerase family member 8 Gene

PARP8 - poly(ADP-ribose) polymerase family member 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：聚 (ADP-核糖) 聚合酶家族成员 8

种属: Homo sapiens

同用名: ARTD16; pART16

基因 ID: 79668 | 基因类型: protein coding

关于 PARP8

This gene has 22 transcripts (splice variants), 207 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 11.4), thyroid (RPKM 9.6) and 24 other tissues.

功能概要

启用蛋白质 ADP-核糖基酶活性。参与蛋白质自身-ADP-核糖基化和蛋白质单-ADP-核糖基化。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein ADP-ribosylase activity. Involved in protein auto-ADP-ribosylation and protein mono-ADP-ribosylation. [provided by Alliance of Genome Resources, Apr 2022]

PARP8 基因产物(4)

mRNA Protein Name
NM_001178055.2 NP_001171526.1 protein mono-ADP-ribosyltransferase PARP8 isoform 1
NM_001178056.2 NP_001171527.1 protein mono-ADP-ribosyltransferase PARP8 isoform 2
NM_001331028.2 NP_001317957.1 protein mono-ADP-ribosyltransferase PARP8 isoform 3
NM_024615.4 NP_078891.2 protein mono-ADP-ribosyltransferase PARP8 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NAD+-protein ADP-ribosyltransferase activity IDA
IDA: 通过直接分析推断
25043379 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein auto-ADP-ribosylation IDA
IDA: 通过直接分析推断
25043379 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein mono-ADP-ribosyltransferase PARP8

ADP-ribosyltransferase diphtheria toxin-like 16

关联疾病

疾病名称 别名
Developmental And Epileptic Encephalopathy 24

DEE24

Epileptic Encephalopathy, Early Infantile, 24

Eiee24

Developmental And Epileptic Encephalopathy, 24

Early Infantile Epileptic Encephalopathy 24

Encephalopathy, Epileptic, Early Infantile, Type 24
Arthrogryposis, Renal Dysfunction, And Cholestasis 1

Arc Syndrome

ARCS1

Arthrogryposis Renal Dysfunction Cholestasis Syndrome

Arthrogryposis-Renal Dysfunction-Cholestasis Syndrome

Arcs

Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome

Arthrogryposis, Renal Dysfunction, And Cholestasis

Arthrogryposis-Renal Dysfunction-Cholestasis

Arthrogryposis - Renal Dysfunction - Cholestasis

Arthrogryposis Multiplex Congenita, Renal Dysfunction, And Cholestasis

Arthrogryposis, Renal Dysfunction And Cholestasis Syndrome 1

Arthrogryposis Renal Dysfunction And Cholestasis 1

Arthrogryposis With Renal Dysfunction And Cholestasis Syndrome

Arthrogryposis, Renal Dysfunction, Cholestasis, Type 1

Kidney Failure

Renal Insufficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10070 PARP8 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PARP8 RGD RGD:1587384
Felis catus PARP8 VGNC VGNC:102281
Mus musculus PARP8 MGD MGI:1098713
Canis familiaris PARP8 VGNC VGNC:49024
Macaca mulatta PARP8 VGNC VGNC:84477
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