1. Gene
  2. ELMO3 - engulfment and cell motility 3 Gene

ELMO3 - engulfment and cell motility 3 Gene

中文名称:吞噬和细胞运动 3

种属: Homo sapiens

同用名: CED12; CED-12; ELMO-3

基因 ID: 79767 | 基因类型: protein coding

关于 ELMO3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,199,131-67,204,004 (from NCBI)

This gene has 6 transcripts (splice variants), 207 orthologues and 5 paralogues. Broad expression in duodenum (RPKM 15.2), skin (RPKM 12.9) and 20 other tissues.

功能概要

该基因编码的蛋白质类似于秀丽隐杆线虫蛋白质,后者在凋亡细胞的吞噬作用和细胞迁移中发挥作用。这个吞噬和细胞运动 (ELMO) 蛋白小家族的其他成员已被证明与细胞分裂蛋白 1 蛋白的奉献者相互作用,以促进吞噬作用并影响细胞形状变化。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]

ELMO3 基因产物(1)

mRNA Protein Name
NM_024712.5 NP_078988.3 engulfment and cell motility protein 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24567399 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ELMO3 蛋白结构

DUF3361

DUF3361: Domain of unknown function (DUF3361) (168 - 322)

ELMO_CED12

ELMO_CED12: ELMO/CED-12 family (343 - 522)

  • 0
  • 200
  • 400
  • 600
  • 773 a.a.
蛋白主名 其他名称

engulfment and cell motility protein 3

ced-12 homolog 3

直系同源

种属 基因名 来源 基因 ID
Mus musculus ELMO3 MGD MGI:2679007
Felis catus ELMO3 VGNC VGNC:61817
Rattus norvegicus ELMO3 RGD RGD:1304734
Canis familiaris ELMO3 VGNC VGNC:40311
Macaca mulatta ELMO3 VGNC VGNC:72060
Bos taurus ELMO3 VGNC VGNC:28440