1. Gene
  2. Itga7 - integrin subunit alpha 7 Gene

Itga7 - integrin subunit alpha 7 Gene

种属: Rattus norvegicus

基因 ID: 81008 | 基因类型: protein coding

关于 Itga7

功能概要

Enables Integrin binding activity and laminin binding activity. Involved in cell adhesion; integrin-mediated signaling pathway; and skeletal muscle tissue development. Located in cell surface. Part of Integrin complex. Used to study cardiomyopathy. Biomarker of arteriosclerosis. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to Integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (Integrin subunit alpha 7). [provided by Alliance of Genome Resources, Apr 2022]

Itga7 基因产物(1)

mRNA Protein Name
NM_030842.1 NP_110469.1 integrin alpha-7 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IDA
IDA: 通过直接分析推断
1315319 RGD
enables integrin binding IPI
IPI: 通过物理相互作用推断
1315319 RGD
enables laminin binding IDA
IDA: 通过直接分析推断
1315319 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20019333 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
1315319 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IDA
IDA: 通过直接分析推断
1315319 RGD
involved in cell adhesion IMP
IMP: 通过突变表型推断
16282198 RGD
involved in integrin-mediated signaling pathway IDA
IDA: 通过直接分析推断
1315319 RGD
involved in skeletal muscle tissue development IEP
IEP: 通过表达模式推断
1315319 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
1315319 RGD
part of integrin complex IDA
IDA: 通过直接分析推断
1315319 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

integrin alpha-7

H36-alpha7

alpha 7A integrin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itga7 NCBI NCBI:3679