Ptger4 - prostaglandin E receptor 4 Gene

种属: Rattus norvegicus

同用名: EP4; Ptger; Ptgerep4

基因 ID: 84023 | 基因类型: protein coding

关于 Ptger4

功能概要

Enables prostaglandin E receptor activity. Involved in several processes, including regulation of circadian sleep/wake cycle, sleep; regulation of cytokine production; and regulation of secretion. Located in several cellular components, including neuron projection terminus; neuronal cell body; and nuclear membrane. Used to study acute kidney failure; cystitis; end stage renal disease; myocarditis; and osteoporosis. Biomarker of retinal ischemia and transient cerebral ischemia. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ptger4 基因产物(1)

mRNA	Protein	Name
NM_032076.3	NP_114465.3	prostaglandin E2 receptor EP4 subtype

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables prostaglandin E receptor activity	IDA IDA: 通过直接分析推断	10336471	RGD

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in ERK1 and ERK2 cascade	IDA IDA: 通过直接分析推断	19233324	RGD
involved in JNK cascade	IDA IDA: 通过直接分析推断	19233324	RGD
involved in bone development	IDA IDA: 通过直接分析推断	19233324	RGD
involved in cAMP biosynthetic process	IMP IMP: 通过突变表型推断	11278900	RGD
involved in cAMP/PKA signal transduction	IMP IMP: 通过突变表型推断	11278900	RGD
involved in cellular response to glucose stimulus	IEP IEP: 通过表达模式推断	12888618	RGD
involved in cellular response to interleukin-1	IEP IEP: 通过表达模式推断	11207665	RGD
involved in cellular response to prostaglandin E stimulus	IEP IEP: 通过表达模式推断	11248657	RGD
involved in cellular response to prostaglandin E stimulus	IMP IMP: 通过突变表型推断	11278900	RGD
involved in chemokinesis	IMP IMP: 通过突变表型推断	8679543	RGD
involved in ductus arteriosus closure	IMP IMP: 通过突变表型推断	16303610	RGD
involved in female pregnancy	IEP IEP: 通过表达模式推断	10819751	RGD
involved in maternal process involved in parturition	IEP IEP: 通过表达模式推断	19801535	RGD
involved in negative regulation of ductus arteriosus closure	IMP IMP: 通过突变表型推断	16303610	RGD
involved in negative regulation of endothelin production	IMP IMP: 通过突变表型推断	15560120	RGD
involved in negative regulation of hydrogen peroxide metabolic process	IMP IMP: 通过突变表型推断	11991626	RGD
involved in negative regulation of interleukin-1 alpha production	IMP IMP: 通过突变表型推断	15560120	RGD
involved in negative regulation of nitric-oxide synthase biosynthetic process	IMP IMP: 通过突变表型推断	11991626	RGD
involved in negative regulation of peptide secretion	IMP IMP: 通过突变表型推断	15560120	RGD
involved in negative regulation of small intestine smooth muscle contraction	IMP IMP: 通过突变表型推断	11991626	RGD
involved in negative regulation of tumor necrosis factor production	IMP IMP: 通过突变表型推断	15560120	RGD
involved in positive regulation of antral ovarian follicle growth	IMP IMP: 通过突变表型推断	15944932	RGD
involved in positive regulation of bone resorption	IMP IMP: 通过突变表型推断	11792579	RGD
involved in positive regulation of calcitonin secretion	IMP IMP: 通过突变表型推断	11278900	RGD
involved in positive regulation of cell adhesion	IMP IMP: 通过突变表型推断	14751573	RGD
involved in positive regulation of cell population proliferation	IMP IMP: 通过突变表型推断	19233324	RGD
involved in positive regulation of chemokinesis	IMP IMP: 通过突变表型推断	8679543	RGD
involved in positive regulation of circadian sleep/wake cycle, non-REM sleep	IMP IMP: 通过突变表型推断	10923657	RGD
involved in positive regulation of gene expression	IMP IMP: 通过突变表型推断	17673547	RGD
involved in positive regulation of hyaluronan biosynthetic process	IMP IMP: 通过突变表型推断	17080198	RGD
involved in positive regulation of interleukin-10 production	IMP IMP: 通过突变表型推断	15560120	RGD
involved in positive regulation of interleukin-8 production	IMP IMP: 通过突变表型推断	15944932	RGD
involved in positive regulation of matrix metallopeptidase secretion	IMP IMP: 通过突变表型推断	8679543	RGD
involved in positive regulation of mucus secretion	IMP IMP: 通过突变表型推断	11991626	RGD
involved in positive regulation of neutrophil extravasation	IMP IMP: 通过突变表型推断	15944932	RGD
involved in positive regulation of ossification	IMP IMP: 通过突变表型推断	14751573	RGD
involved in positive regulation of osteoblast differentiation	IMP IMP: 通过突变表型推断	14751573	RGD
involved in positive regulation of ovarian follicle development	IMP IMP: 通过突变表型推断	15944932	RGD
involved in positive regulation of protein modification process	IMP IMP: 通过突变表型推断	17067562	RGD
involved in positive regulation of protein secretion	IMP IMP: 通过突变表型推断	8679543	RGD
involved in positive regulation of smooth muscle cell migration	IMP IMP: 通过突变表型推断	17080198	RGD
involved in positive regulation of substance P secretion	IMP IMP: 通过突变表型推断	11278900	RGD
involved in positive regulation of substance P secretion, neurotransmission	IMP IMP: 通过突变表型推断	15292051	RGD
involved in positive regulation of urine volume	IMP IMP: 通过突变表型推断	18287210	RGD
involved in positive regulation of wound healing	IMP IMP: 通过突变表型推断	16515909	RGD
involved in regulation of circadian sleep/wake cycle, wakefulness	IMP IMP: 通过突变表型推断	10923657	RGD
involved in response to amino acid	IEP IEP: 通过表达模式推断	10882227	RGD
involved in response to interleukin-1	IEP IEP: 通过表达模式推断	10800959	RGD
involved in response to organic cyclic compound	IEP IEP: 通过表达模式推断	19801535	RGD
involved in response to progesterone	IEP IEP: 通过表达模式推断	19801535	RGD
involved in response to prostaglandin E	IEP IEP: 通过表达模式推断	10800959	RGD
involved in response to salt	IEP IEP: 通过表达模式推断	10432392	RGD
involved in response to water-immersion restraint stress	IEP IEP: 通过表达模式推断	10882227	RGD
involved in response to xenobiotic stimulus	IEP IEP: 通过表达模式推断	10800959	RGD

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in neuron projection terminus	IDA IDA: 通过直接分析推断	15292051	RGD
located in neuronal cell body	IDA IDA: 通过直接分析推断	15292051	RGD
located in nuclear membrane	IDA IDA: 通过直接分析推断	10336471	RGD

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

prostaglandin E2 receptor EP4 subtype

PGE receptor, EP4 subtype	PGE2 receptor EP4 subtype
prostaglandin E receptor 4 (subtype EP4)	prostaglandin E2 receptor type 4
prostanoid EP4 receptor

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11378	PTGER4 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS18874	Ptger4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS25365	Ptger4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Ptger4	NCBI	NCBI:5734

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

粤ICP备2021105330号-3

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Ptger4 - prostaglandin E receptor 4 Gene

关于 Ptger4

功能概要

Ptger4 基因产物(1)

直系同源

热门区域

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Ptger4 - prostaglandin E receptor 4 Gene

关于 Ptger4

功能概要

Ptger4 基因产物(1)

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z