2. Gene
  3. ABLIM2 - actin binding LIM protein family member 2 Gene

ABLIM2 - actin binding LIM protein family member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：肌动蛋白结合 LIM 蛋白家族成员 2

种属: Homo sapiens

基因 ID: 84448 | 基因类型: protein coding

关于 ABLIM2

Cytogenetic location: 4p16.1 Genomic coordinates (GRCh38): 4:7,965,327-8,158,813 (from NCBI)

This gene has 16 transcripts (splice variants), 201 orthologues and 3 paralogues. Broad expression in spleen (RPKM 7.8), brain (RPKM 4.6) and 16 other tissues.

功能概要

预测启用肌动蛋白丝结合活性。预计参与片状足的组装。预计在 RNA 聚合酶 II 的转录正调控上游或正调控内起作用。位于肌动蛋白细胞骨架中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

ABLIM2 基因产物(8)

mRNA Protein Name
NM_001130083.2 NP_001123555.1 actin-binding LIM protein 2 isoform 1
NM_001130084.2 NP_001123556.1 actin-binding LIM protein 2 isoform 2
NM_001130085.2 NP_001123557.1 actin-binding LIM protein 2 isoform 3
NM_001130086.2 NP_001123558.1 actin-binding LIM protein 2 isoform 4
NM_001130087.2 NP_001123559.1 actin-binding LIM protein 2 isoform 5
NM_001130088.2 NP_001123560.1 actin-binding LIM protein 2 isoform 7
NM_001286688.2 NP_001273617.1 actin-binding LIM protein 2 isoform 8
NM_032432.5 NP_115808.3 actin-binding LIM protein 2 isoform 6
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26871637 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
17194709 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ABLIM2 蛋白结构

LIM

LIM: LIM domain (24 - 78)

LIM

LIM: LIM domain (83 - 135)

LIM

LIM: LIM domain (153 - 208)

LIM

LIM: LIM domain (212 - 255)

VHP

VHP: Villin headpiece domain (576 - 611)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 611 a.a.
蛋白主名 其他名称

actin-binding LIM protein 2

abLIM-2

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00107 ABLIM2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ABLIM2 VGNC VGNC:69474
Canis familiaris ABLIM2 VGNC VGNC:37479
Felis catus ABLIM2 VGNC VGNC:59490
Bos taurus ABLIM2 VGNC VGNC:25508
Mus musculus ABLIM2 MGD MGI:2385758
Rattus norvegicus ABLIM2 RGD RGD:1303094
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