CNTNAP4 - contactin associated protein family member 4 Gene

中文名称：接触素相关蛋白家族成员 4

种属: Homo sapiens

同用名: CASPR4

关于 CNTNAP4

功能概要

该基因编码 neurexin 蛋白家族的一个成员。这个家族的成员在脊椎动物神经系统中作为细胞粘附分子和受体发挥作用。该蛋白质包含表皮生长因子重复序列和层粘连蛋白 G 结构域。此外，它还包括 F5/8 C 型结构域、盘状蛋白/神经毡蛋白和纤维蛋白原样结构域，以及血小板反应蛋白 N 末端样结构域。这种蛋白质还可能在多巴胺能和 GABA 能系统的正常神经传递中发挥作用，并且该基因的突变可能与某些精神疾病有关。该基因内含子的多态性可能与长寿有关。[RefSeq 提供，2016 年 4 月]

This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016]