2. Gene
  3. Ciita - class II, major histocompatibility complex, transactivator Gene

Ciita - class II, major histocompatibility complex, transactivator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: C2ta; Mhc2ta

基因 ID: 85483 | 基因类型: protein coding

关于 Ciita

功能概要

Predicted to enable DNA-binding transcription factor binding activity; protein C-terminus binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to electrical stimulus; cellular response to exogenous dsRNA; and regulation of macromolecule biosynthetic process. Located in cell surface. Used to study periapical periodontitis. Human ortholog(s) of this gene implicated in Addison's disease; MHC class II deficiency; autoimmune disease (multiple); and myocardial infarction. Orthologous to human CIITA (class II major histocompatibility complex transactivator). [provided by Alliance of Genome Resources, Apr 2022]

Ciita 基因产物(3)

mRNA Protein Name
NM_001270803.1 NP_001257732.1 MHC class II transactivator isoform 2
NM_001270804.1 NP_001257733.1 MHC class II transactivator isoform 3
NM_053529.2 NP_445981.2 MHC class II transactivator isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to electrical stimulus IEP
IEP: 通过表达模式推断
10051633 RGD
involved in cellular response to exogenous dsRNA IEP
IEP: 通过表达模式推断
10051633 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
11071855 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11071855 RGD
involved in positive regulation of MHC class II biosynthetic process IDA
IDA: 通过直接分析推断
11071855 RGD
involved in positive regulation of MHC class II biosynthetic process IEP
IEP: 通过表达模式推断
11477547 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11071855 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
23524893 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

MHC class II transactivator

MHC class II transactivator type IV

class II transactivator

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02714 CIITA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19181 Ciita Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25669 Ciita Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ciita NCBI NCBI:4261
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