BTAF1 - B-TFIID TATA-box binding protein associated factor 1 Gene

中文名称：B-TFIID TATA 盒结合蛋白相关因子 1

种属: Homo sapiens

同用名: MOT1; TAF172; TAFII170; TAF(II)170

关于 BTAF1

功能概要

该基因编码一个 TAF (TATA 盒结合蛋白相关因子) ，它与 TBP (TATA 盒结合蛋白) 结合形成 B-TFIID 复合物，该复合物是 RNA 聚合酶 II 启动基因转录所必需的。该 TAF 具有 DNA 依赖性 ATP 酶活性，可驱动 TBP 从 DNA 中解离，从而使 TBP 与其他 TATA 盒或无 TATA 启动子结合。[RefSeq 提供，2011 年 9 月]

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with Other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]