MTRF1 - mitochondrial translation release factor 1 Gene

中文名称：线粒体翻译释放因子 1

种属: Homo sapiens

同用名: RF1; MRF1; MTTRF1

关于 MTRF1

功能概要

由该基因编码的蛋白质通过计算机方法确定为线粒体蛋白质，与在细菌和酵母中发现的肽链释放因子 (RF) 具有相似性。肽链释放因子响应肽链终止密码子指导翻译终止。最初被认为在终止线粒体蛋白质合成中起作用，最近的一份出版物发现没有线粒体翻译释放功能。 mRNA 和 EST 数据表明存在多个选择性剪接的转录本变体；但是，它们的全长性质尚不清楚。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq, Jul 2008]