1. Gene
  2. Hrh3 - histamine receptor H3 Gene

Hrh3 - histamine receptor H3 Gene

中文名称:组胺受体H3

种属: Mus musculus

同用名: H3R; Eae8; HH3R

基因 ID: 99296 | 基因类型: protein coding

关于 Hrh3

Chromosome 2: 179,741,258-179,746,281 reverse strand.GRCm39:CM000995.3

This gene has 8 transcripts (splice variants), 117 orthologues, 32 paralogues and is associated with 26 phenotypes. Biased expression in frontal lobe adult (RPKM 17.2), cortex adult (RPKM 16.) and 8 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联胺受体活性;胺结合活性;和杂环化合物结合活性。预计参与多个过程,包括G蛋白偶联受体信号通路;学习或记忆;和分泌调节。预测作用于 G 蛋白偶联受体信号通路的上游或内部。预测位于髓鞘内;神经元投射;和质膜。预计在树突和突触中活跃。预计是质膜的组成部分。在大脑中表达。与人类 HRH3(组胺受体 H3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled amine receptor activity; amine binding activity; and heterocyclic compound binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; learning or memory; and regulation of secretion. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in myelin sheath; neuron projection; and plasma membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Is expressed in brain. Orthologous to human HRH3 (Histamine Receptor H3). [provided by Alliance of Genome Resources, Apr 2022]

Hrh3 基因产物(9)

mRNA Protein Name
NM_001409452.1 NP_001396381.1 histamine H3 receptor isoform 3
NM_001409453.1 NP_001396382.1 histamine H3 receptor isoform 4
NM_001409454.1 NP_001396383.1 histamine H3 receptor isoform 5
NM_001409456.1 NP_001396385.1 histamine H3 receptor isoform 2 precursor
NM_133849.4 NP_598610.1 histamine H3 receptor isoform 1
NM_001409457.1 NP_001396386.1 histamine H3 receptor isoform 2 precursor
NM_001409451.1 NP_001396380.1 histamine H3 receptor isoform 2 precursor
NM_001409458.1 NP_001396387.1 histamine H3 receptor isoform 2 precursor
NM_001409455.1 NP_001396384.1 histamine H3 receptor isoform 6

Hrh3 蛋白结构

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (47 - 422)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (68 - 95)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (106 - 136)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (151 - 169)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (194 - 224)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (350 - 380)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (390 - 415)

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  • 400
  • 445 a.a.
蛋白主名 其他名称

histamine H3 receptor

experimental allergic encephalomyelitis susceptibility 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hrh3 NCBI NCBI:11255