2. Anti-infection
  3. Bacterial
  4. GlcB-IN-1

GlcB-IN-1 是一种结核分枝杆菌苹果酸合酶 (GlcB) 抑制剂，IC50 为 1.05 μM。GlcB-IN-1 可用于结核病的研究。

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GlcB-IN-1

GlcB-IN-1 Chemical Structure

CAS No. : 1346745-52-5

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GlcB-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GlcB-IN-1 is an inhibitor of Mycobacterium malate synthase (GlcB) with an IC50 of 1.05 μM. GlcB-IN-1 can be used for the research of tuberculosis[1].

体外研究
(In Vitro)

GlcB-IN-1 (compound 19) 结合于结核分枝杆菌苹果酸合酶 (GlcB)，形成的复合物保留了闭合的活性位点盖和“向内”的 CoA 结合环构象，并与 Met-631 形成弱氢键[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

GlcB-IN-1 相关抗体:
分子量

231.20

Formula

C12H9NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GlcB-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GlcB-IN-11346745-52-5BacterialtuberculosisCoA binding loopMycobacterium tuberculosisMet-631GlcBmalate synthaseInhibitorinhibitorinhibit

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