2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. HDZI 2,4OH

HDZI 2,4OH 通过 GABA 受体发挥显著的抗焦虑活性。HDZI 2,4OH 可以透过血脑屏障。HDZI 2,4OH 在斑马鱼体内表现出低毒性。HDZI 2,4OH 可以用于焦虑症等神经系统疾病的研究。

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HDZI 2,4OH

HDZI 2,4OH Chemical Structure

CAS No. : 263153-49-7

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HDZI 2,4OH 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HDZI 2,4OH exerts significant anti anxiety activity through GABA receptors. HDZI 2,4OH can penetrate the blood-brain barrier. HDZI 2,4OH exhibits low toxicity in zebrafish. HDZI 2,4OH can be used for research on neurological disorders such as anxiety disorders[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 EC50
4 μM
Compound: 4
Cytotoxicity against human HCT116 p53 +/+ and -/- cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 p53 +/+ and -/- cells after 72 hrs by MTT assay
[PMID: 23306052]
分子量

257.24

Formula

C13H11N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HDZI 2,4OH 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDZI 2,4OH263153-49-7GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorGABAneurologicalanxietyInhibitorinhibitorinhibit

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