1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. HexylHIBO hydrobromide

HexylHIBO hydrobromide 是一种 I 型 mGluR 拮抗剂,在 mGlu1a和 mGlu5a 受体的 Kb 值为 140 μM 和 110 μM。HexylHIBO hydrobromide 不抑制 mGlu2 和 mGlu4a。HexylHIBO hydrobromide 降低大鼠自发兴奋性突触后电流 (sEPSC)。

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HexylHIBO hydrobromide

HexylHIBO hydrobromide Chemical Structure

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规格 是否有货
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100 mg   询价  
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HexylHIBO hydrobromide 的其他形式现货产品:

Customer Review

Other Forms of HexylHIBO hydrobromide:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HexylHIBO hydrobromide is a potent group I mGluR antagonist with Kbs of 140 μM and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO hydrobromide does not inhibits mGlu2 and mGlu4a. HexylHIBO hydrobromide decreases spontaneous excitatory postsynaptic currents (sEPSCs) in rat[1][2].

IC50 & Target[1][2]

mGluR1a

140 μM (Kb)

mGluR5a

110 μM (Kb)

分子量

337.21

Formula

C12H21BrN2O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

HexylHIBO hydrobromide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HexylHIBO hydrobromide
目录号:
HY-175100
需求量: