1. Anti-infection
  2. HIV
  3. HIV-1-IN-93

HIV-1-IN-93 是一种 HIV-1 RNase H 抑制剂,IC50 为 6.09 μM。HIV-1-IN-93 细胞毒性较低,可用于 HIV-1 感染相关研究。

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HIV-1-IN-93

HIV-1-IN-93 Chemical Structure

CAS No. : 2366269-07-8

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生物活性

HIV-1-IN-93 is a HIV-1 RNase H inhibitor with an IC50 of 6.09 μM. HIV-1-IN-93 shows low cytotoxicity and can be used in studies related to HIV-1 infection[1].

体外研究
(In Vitro)

HIV-1-IN-93 (compound I-4) (5 days) 在 MT-4 细胞中未表现出显著的抗 HIV-1 (IIIB) 或抗 HIV-2 (ROD) 活性,且在该细胞中的细胞毒性较低[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MT-4 cells infected with wild-type HIV-1 (IIIB) or HIV-2 (ROD)
Concentration: /
Incubation Time: 5 days
Result: Did not exhibit significant anti-HIV activity against HIV-1 (IIIB) or HIV-2 (ROD) at the highest concentration tested, with EC50 values >315.9 µM for both strains.
Showed low cytotoxicity, with a CC50 value of 315.9 µM in MT-4 cells.
分子量

365.27

Formula

C16H10F3N3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HIV-1-IN-93
目录号:
HY-183157
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