2. Anti-infection
  3. HIV
  4. Hydroxydihydrobovolide

Hydroxydihydrobovolide 是一种被发现存在于 Portulaca oleracea L. 中的 α,β-不饱和 γ-内酯。Hydroxydihydrobovolide 对癌细胞表现出细胞毒性，并具有抗 HIV-1 活性 (IC50 = 122.7 μM)。Hydroxydihydrobovolide 可用于神经母细胞瘤和 HIV-1 感染的相关研究。

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Hydroxydihydrobovolide

Hydroxydihydrobovolide Chemical Structure

CAS No. : 1403940-81-7

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Hydroxydihydrobovolide 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection[1].

IC50 & Target[1]

HIV-1

122.7 μM (IC50)

体外研究
(In Vitro)

Hydroxydihydrobovolide (Compound HDB) (0.01-50 μM；48 h) 在 50 μM 浓度下对 SH-SY5Y 细胞具有显著细胞毒性[1]。
Hydroxydihydrobovolide 可抑制 HIV-1 复制，其 IC50 为 122.7 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Hydroxydihydrobovolide 相关抗体:

Cell Viability Assay[1]

Cell Line: SH-SY5Y human neuroblastoma cells
Concentration: 0.01, 0.1, 1, 10, 50 μM
Incubation Time: 48 h
Result: Did not cause a statistically significant decrease in SH-SY5Y cell viability at 0.01-10 μM.
Significantly inhibited SH-SY5Y cell growth at 50 μM.
分子量

198.26

Formula

C11H18O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hydroxydihydrobovolide 相关分类

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Keywords:

Hydroxydihydrobovolide1403940-81-7HIVHuman immunodeficiency virusPortulaca oleracea L.neuroblastomaanti-HIVSH-SY5Y cellsInhibitorinhibitorinhibit

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