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  3. Fluorescent Dye
  4. ICAAc

ICAAc 是一种碱性降低的溶剂致变色荧光团。ICAAc 在不同极性的溶剂中表现出显著的溶剂致变色行为；在水中，它具有较大的偶极矩差异和较低的量子产率，这使其成为一种可调谐的溶剂致变色荧光团。ICAAc 可通过紫外-可见光谱/荧光检测实现 pH 传感，并适用于包括十二烷基硫酸钠胶束 Stern 层在内的微环境检测。ICAAc 可作为一种活体细胞染色剂，用于活体癌细胞的落射荧光成像。

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ICAAc

ICAAc Chemical Structure

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ICAAc 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ICAAc is a solvatochromic fluorophore with reduced basicity. ICAAc demonstrates significant solvatochromic behavior across solvents of varying polarity, with a large dipole moment difference and low quantum yield in water, making it a tunable solvatochromic fluorophore. ICAAc enables pH sensing via UV-vis/fluorescence detection and in microenvironments including sodium lauryl sulfate micelle Stern layers. ICAAc acts as a supravital cell stain for epifluorescence imaging of live cancer cells[1].

体外研究
(In Vitro)

ICAAc 可在水性缓冲溶液中作为稳定、精准的生理 pH 探针，其 pKa 值为 7.05，能够在 pH 6-8 的生理范围内实现准确的 pH 检测[1]。
ICAAC (0.3 μg/mL; incubation for imaging) 适合作为活 HeLa 细胞常规落射荧光成像的体外活细胞染色剂，使用浓度为 0.3 μg/mL[1]。
随着溶剂极性的增加，ICAAc 的发射波长会随之增加。在水、二氧六环和正己烷中，其激发/发射最大值分别为 466/553 nm、431/515 nm 和 418/503 nm。ICAAc 的吸收最大值随 pH 值的升高而降低[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ICAAc 相关抗体:
分子量

219.24

Formula

C14H9N3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ICAAc 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ICAAcFluorescent Dyelive cancer cellssupravital cell stainsodium lauryl sulfate micelle Stern layerssolvatochromic fluorophoreUV-vis/fluorescence detectionHeLa cellscytotoxic agentphysiological pH probeepifluorescence imagingaqueous buffer solutionsInhibitorinhibitorinhibit

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