2. Immunology/Inflammation
  3. NO Synthase
  4. Idesin

Idesin 是一种被发现存在于山桐子 (Idesia polycarpa) 果实中的化合物。Idesin 可抑制 LPS (HY-D1056) 诱导的一氧化氮生成，且仅具有轻微的细胞毒性。

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Idesin

Idesin Chemical Structure

CAS No. : 20331-85-5

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Idesin 相关抗体

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Idesin is a compound found in the fruits of Idesia polycarpa. Idesin inhibits LPS (HY-D1056)-induced nitric oxide production with mild cytotoxicity[1].

体外研究
(In Vitro)

Idesin (Compound 4) (1-100 μM; 25 h) 可显著抑制 LPS (HY-D1056) 诱导的 BV2 小胶质细胞中 NO 的生成，在 100 μM 浓度下仅表现出轻微的细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Idesin 相关抗体:

Cell Viability Assay[1]

Cell Line: BV2 mouse microglial cells (LPS-stimulated)
Concentration: 1 μM, 10 μM, 100 μM
Incubation Time: 25 h total (1 h pre-treatment + 24 h co-incubation with LPS)
Result: Reduced nitrite levels to 7.0 ± 0.1 μM and resulted in 87.2 ± 4.2% cell viability at 1 μM.
Reduced nitrite levels to 5.5 ± 0.3 μM and resulted in 97.6 ± 6.3% cell viability at 10 μM.
Reduced nitrite levels to 4.9 ± 0.5 μM and resulted in 90.7 ± 6.8% cell viability at 100 μM.
分子量

302.28

Formula

C13H18O8
CAS 号
中文名称

山桐子苷
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Idesin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Idesin20331-85-5山桐子苷NO SynthaseNitric oxide synthasesNOSnitric oxideIdesia polycarpamicrogliaBV2 microglial cellslipopolysaccharideInhibitorinhibitorinhibit

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