2. 天然产物
  3. 植物 其他类
  4. 桔梗科
  5. 半边莲
  6. Isolobetyol

Isolobetyol 是被发现存在于半边莲 (Lobelia chinensis) 全株中的一种聚乙炔类化合物。Isolobetyol 对癌细胞表现出细胞毒性作用。Isolobetyol 可用于癌症研究，例如人类肺癌和双相型间皮瘤的研究。

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Isolobetyol

Isolobetyol Chemical Structure

CAS No. : 1621230-88-3

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Isolobetyol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isolobetyol is a polyacetylene found in whole plants of Lobelia chinensis. Isolobetyol shows cytotoxic effects against cancer cells. Isolobetyol can be used for the research of cancer, such as human lung cancer and biphasic mesothelioma[1].

体外研究
(In Vitro)

Isolobetyol (48 h) 对 MSTO-211H 双相型间皮瘤细胞和 NCI-H292 人肺黏液表皮样癌细胞表现出中等细胞毒活性，其 IC50 值分别为 12.36 μM 和 9.31 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Isolobetyol 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: NCI-H292 human lung mucoepidermoid carcinoma cells, MSTO-211H biphasic mesothelioma cells
Concentration: IC50 9.31 μM (NCI-H292); IC50 12.36 μM (MSTO-211H)
Incubation Time: 48 h
Result: Exhibited moderate cytotoxic activity with an IC50 of 12.36 μM against MSTO-211H cells.
Showed moderate cytotoxic activity with an IC50 of 9.31 μM against NCI-H292 cells.
分子量

234.29

Formula

C14H18O3
CAS 号
中文名称

异党参炔醇
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Isolobetyol 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isolobetyol1621230-88-3异党参炔醇Othershuman lung cancerbiphasic mesothelioma cellshuman lung cancer cellshuman lung mucoepidermoid carcinomaMSTO-211HpolyacetyleneNCI-H292Lobelia chinensisInhibitorinhibitorinhibit

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