2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. IT 066 hydrochloride

IT 066 hydrochloride 是一种组胺 H2 受体拮抗剂。IT 066 hydrochloride 具有抗氧化活性，能够保护大鼠免受缺血再灌注诱导的急性胃黏膜损伤。IT 066 hydrochloride 在大鼠中也能够抑制促分泌素诱导的胃酸分泌，对大鼠实验性胃、十二指肠损伤具有长效抗损伤作用。IT 066 hydrochloride 可用于胃肠道疾病的研究。

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IT 066 hydrochloride

IT 066 hydrochloride Chemical Structure

CAS No. : 126463-66-9

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IT 066 hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Histamine Receptor 亚型特异性产品:

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IT 066 hydrochloride is a Histamine H2 receptor antagonist. IT 066 hydrochloride possesses antioxidant activity and can protect rats against acute gastric mucosal injury induced by ischemia-reperfusion. IT 066 hydrochloride can also inhibit secretagogue-induced gastric acid secretion in rats and exert a long-acting anti-lesion effect on experimental gastric and duodenal lesions in rats. IT 066 hydrochloride is applicable for the research of gastrointestinal diseases[1][2].

分子量

392.88

Formula

C19H25ClN4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IT 066 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IT 066126463-66-9IT066IT-066Histamine ReceptorParietal cellsischemia-reperfusionacute gastric mucosal injury modelInhibitorinhibitorinhibit

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IT 066 hydrochloride
目录号：
HY-19105A
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