2. Others
  3. Drug Derivative
  4. Jasplakinolide probe-1

Jasplakinolide probe-1 (Compound 12) 是 Jasplakinolide (HY-P0027) 的衍生物，是一种 Jasplakinolide 探针。Jasplakinolide probe-1 具有抗增殖活性，能够抑制肌动蛋白的动态变化，导致细胞片足塌陷，干扰肌动蛋白的动态平衡。Jasplakinolide probe-1 与荧光染料偶联后可用于细胞中 actin 结构的成像。

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Jasplakinolide probe-1

Jasplakinolide probe-1 Chemical Structure

CAS No. : 1377338-26-5

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Jasplakinolide probe-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Jasplakinolide probe-1 (Compound 12), a Jasplakinolide (HY-P0027) derivative, is a Jasplakinolide probe. Jasplakinolide probe-1 shows anti-proliferative activity and can inhibit the dynamics of actin, cause the collapse of cell lamellipodia, interfering with the dynamic balance of actin. Jasplakinolide probe-1 can be used for imaging of actin structure in cells conjugated with a fluorescent dye [1].

体外研究
(In Vitro)

Jasplakinolide probe-1 对 MCF-7 (乳腺癌细胞) 和 HT-29 (结直肠癌细胞) 表现出强烈的细胞毒性，其 IC50 值分别为 39 nM 和 10 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Jasplakinolide probe-1 相关抗体:
分子量

773.96

Formula

C43H59N5O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Jasplakinolide probe-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Jasplakinolide probe-11377338-26-5Jasplakinolide probe1Jasplakinolide probe 1Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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目录号：
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