2. Anti-infection
  3. Bacterial
  4. (KFF)3K-acpP

(KFF) 3K-acpP 是一种由细胞穿膜肽 (KFF) 3K (HY-P10556) 与 acpP 肽核酸偶联的抗菌剂。(KFF) 3K-acpP 可结合至 acpP mRNA 的翻译起始位点区域，通过空间位阻阻断核糖体结合并抑制酰基载体蛋白的翻译。(KFF) 3K-acpP 可诱导细菌包膜应激反应通路，并触发外膜蛋白 F (ompF) 转录本的消耗。(KFF) 3K-acpP 可用于感染相关研究。

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Custom Peptide Synthesis

(KFF)3K-acpP

(KFF)3K-acpP Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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(KFF)3K-acpP 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(KFF)3K-acpP is an antibacterial agent conjugating of cell penetrating peptide (KFF)3K (HY-P10556) and acpP
peptide nucleic acid. (KFF)3K-acpP binds to the translation start site region of acpP mRNA, sterically blocking ribosome binding and inhibiting translation of the acyl carrier protein. (KFF)3K-acpP induces bacterial envelope stress response pathways, and triggers depletion of outer membrane protein F (ompF) transcript. (KFF)3K-acpP can be used for the research of infections[1].

体外研究
(In Vitro)

(KFF) 3K-acpP (1.25 μM; 24 h) 可抑制 UPEC 536 的可见生长，其 MIC 为 1.25 μM[1]。
(KFF) 3K-acpP (5 μM; 15 min) 处理 UPEC 536 会导致 acpP mRNA 水平下降 4.8 倍，同时还会引发脱靶转录本减少以及包膜应激反应通路的激活[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(KFF)3K-acpP 相关抗体:

RT-PCR[1]

Cell Line: UPEC 536
Concentration: 5 μM
Incubation Time: 15 min
Result: Caused a 4.8-fold depletion of acpP mRNA.
Sequence

Peptide-PNA:KFFKFFKFFK-CTCATACTCT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(KFF)3K-acpP 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(KFF)3K-acpPBacterialUPEC 536acpP mRNAuropathogenicInhibitorinhibitorinhibit

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产品名称：
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目录号：
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