2. Anti-infection
  3. Bacterial
  4. KIKIKPWWWPKIKIK-NH2

KIKIKPWWWPKIKIK-NH2 是一种 β-转角抗菌肽。KIKIKPWWWPKIKIK-NH2 可抑制细菌生物膜形成并结合脂多糖。KIKIKPWWWPKIKIK-NH2 在小鼠细菌感染全层伤口模型中展现出伤口愈合能力。KIKIKPWWWPKIKIK-NH2 可用于细菌感染的相关研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

KIKIKPWWWPKIKIK-NH2

KIKIKPWWWPKIKIK-NH2 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

KIKIKPWWWPKIKIK-NH2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KIKIKPWWWPKIKIK-NH2 is a β-turn antimicrobial peptide. KIKIKPWWWPKIKIK-NH2 can inhibit bacterial biofilm formation and bind to lipopolysaccharid. KIKIKPWWWPKIKIK-NH2 shows wound-healing ability in mice bacteria-infected full-thickness wound models. KIKIKPWWWPKIKIK-NH2 can be used for the research of bacterial infection[1].

体外研究
(In Vitro)

KIKIKPWWWPKIKIK-NH2 (Compound P-07) (18 h) 对革兰氏阳性菌和革兰氏阴性菌株 (包括多重耐药菌株) 展现出广谱抗菌活性，其几何平均 MIC 为 5.00 μM[1]。
KIKIKPWWWPKIKIK-NH2 (1 h) 对人红细胞的溶血活性较低，其 HC10 大于 256 μM[1]。
KIKIKPWWWPKIKIK-NH2 (2-256 μM；24 h) 对 BEAS-2B、HEK-293T 和 LO2 人细胞系表现出低细胞毒性[1]。
KIKIKPWWWPKIKIK-NH2 (8-16 μM；6 h) 对多重耐药 (MDR) 的金黄色葡萄球菌 (S. aureus) 和多重耐药 (MDR) 的大肠杆菌 (E. coli) 表现出快速的时间依赖性杀菌活性[1]。
KIKIKPWWWPKIKIK-NH2 (2-32 μM; 24 h) 以剂量依赖方式抑制多重耐药 (MDR) 金黄色葡萄球菌 (S. aureus) 和多重耐药 (MDR) 大肠杆菌 (E. coli) 的生物膜形成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

KIKIKPWWWPKIKIK-NH2 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: Human bronchial epithelioid (BEAS-2B), human embryonic kidney (HEK-293T), human hepatic (LO2) cell lines
Concentration: 2, 4, 8, 16, 32, 64, 128, 256 μM
Incubation Time: 24 h
Result: Exhibited low cytotoxicity against BEAS-2B, HEK-293T, and LO2 cells relative to controls.
体内研究
(In Vivo)

KIKIKPWWWPKIKIK-NH2 (Compound P-07) (100 μM；局部给药；每日 1 次；连续 11 天) 可降低小鼠 E. coli 感染伤口模型中的细菌载量与炎症反应，促进伤口愈合[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: KM (Male, 6 weeks old, ~20 g, full-thickness wound infected with E. coli ATCC 25922 and MDR E. coli)[1]
Dosage: 100 μM
Administration: Topical; daily; 11 days
Result: Significantly reduced bacterial loads of E. coli ATCC 25922 and E. coli (MDR) on wound surfaces compared to controls.
Promoted wound healing, with wounds showing smaller sizes over time and almost complete healing by day 11.
Reduced inflammatory cell infiltration, vascular congestion, and IL-6 expression in treated wounds.
分子量

1991.55

Formula

C103H163N25O15
Sequence

Lys-Ile-Lys-Ile-Lys-Pro-Trp-Trp-Trp-Pro-Lys-Ile-Lys-Ile-Lys-NH2
Sequence Shortening

KIKIKPWWWPKIKIK-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KIKIKPWWWPKIKIK-NH2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KIKIKPWWWPKIKIK-NH2BacterialLO2E. coliGram-positive bacterial strainsmultidrug-resistant bacteriaBEAS-2BGram-negative bacterial strainsHEK-293TInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
KIKIKPWWWPKIKIK-NH2
目录号：
HY-P11592
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z