2. Anti-infection
  3. HIV
  4. KP-1212

KP-1212 是一种核苷。KP-1212 通过诱变病毒基因组发挥其抗病毒作用。KP-1212 抑制 HIV 生长。

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KP-1212

KP-1212 Chemical Structure

CAS No. : 114522-16-6

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KP-1212 相关抗体

Top Publications Citing Use of Products

查看 HIV 亚型特异性产品:

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KP-1212 is a nucleoside. KP-1212 exerts its antiviral effect by mutagenizing the viral genome. KP-1212 inhibits HIV growth[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
U373-MAGI EC50
21.6 nM
Compound: KP-1212
Potentiation of gemcitabine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 5 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of gemcitabine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 5 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
[PMID: 24120088]
U373-MAGI EC50
248 μM
Compound: KP-1212
Potentiation of deferoxamine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of deferoxamine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
[PMID: 24120088]
U373-MAGI EC50
52.8 μM
Compound: KP-1212
Potentiation of resveratrol-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of resveratrol-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
[PMID: 24120088]
分子量

230.22

Formula

C8H14N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

KP-1212 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KP-1212114522-16-6DHDAC SN-1212KP1212KP 1212SN1212SN 1212SN-1212HIVHuman immunodeficiency virusantiviralInhibitorinhibitorinhibit

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产品名称：
KP-1212
目录号：
HY-106252
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