2. Metabolic Enzyme/Protease
  3. Thrombin
  4. L 373890

L 373890 是一种选择性吡啶酮乙酰胺类凝血酶 (thrombin) 抑制剂，Ki 值为 0.5 nM。L 373890 对凝血酶的选择性远高于胰蛋白酶 (Ki 值为 570 nM)、丝氨酸蛋白酶、纤溶酶、tPA、活化蛋白 C、血浆激肽释放酶和糜蛋白酶。L 373890 可用于血栓形成研究。

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L 373890

L 373890 Chemical Structure

CAS No. : 187162-33-0

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L 373890 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L 373890 is a selective pyridinone acetamide thrombin inhibitor with a Ki of 0.5 nM. L 373890 shows highly selectivity for thrombin over trypsin (Ki of 570 nM), serine proteases plasmin, tPA, activated protein C, plasma kallikrein and chymotrypsin. L 373890 can be used for thrombosis research[1].

体内研究
(In Vivo)

在 Ferric chloride (HY-Y0266) 诱导的大鼠动脉血栓模型中，以 10 μg/kg/min 的静脉输注速率，L 373890 可有效阻止血管阻塞[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

474.58

Formula

C22H30N6O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L 373890 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L 373890187162-33-0L373890L-373890Thrombinthrombosisthrombin inhibitorInhibitorinhibitorinhibit

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