2. Metabolic Enzyme/Protease Apoptosis Immunology/Inflammation NF-κB
  3. Lactate Dehydrogenase Apoptosis Reactive Oxygen Species (ROS) SOD
  4. LDH-IN-5

LDH-IN-5 是一种具有神经保护活性的乳酸脱氢酶 (LDH) 抑制剂。LDH-IN-5 能够抑制细胞凋亡 (apoptosis)，减少活性氧 (ROS)、丙二醛 (MDA) 的产生，并提高超氧化物歧化酶 (SOD) 的活性。LDH-IN-5 可用于神经系统疾病的研究，如缺血性脑卒中。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

LDH-IN-5

LDH-IN-5 Chemical Structure

CAS No. : 2768522-31-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

LDH-IN-5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LDH-IN-5 is a Lactate Dehydrogenase (LDH) inhibitor with neuroprotective activity. LDH-IN-5 can inhibit cell apoptosis, reduce ROS, MDA production and increases superoxide dismutase (SOD) activity. LDH-IN-5 can be used for the research of neurological disease, such as ischemic stroke[1].

体外研究
(In Vitro)

LDH-IN-5 (Compound s6b) (12.5-50 μM, 6h) 可显著提高小鼠海马神经元 HT22 细胞的存活率，并减少 LDH 的释放[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LDH-IN-5 相关抗体:
体内研究
(In Vivo)

LDH-IN-5 (Compound s6b) (125-500 μg/mL, 18 h) 可显著降低由 Ponatinib (HY-12047) 诱导的 2dpf 白化斑马鱼模型中脑血栓的发生率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 2dpf albino zebrafish models induced by Ponatinib (HY-12047)[1]
Dosage: 125-500 μg/mL
Administration: 18 h
Result: Showed the thrombosis incidence decreases by 97% in the 125 μg/mL dose group and 77% in the 500 μg/mL dose group.
Showed no zebrafish death or obvious toxicity at 500 μg/mL.
分子量

659.69

Formula

C36H51BrO6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LDH-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDH-IN-52768522-31-0Lactate DehydrogenaseApoptosisReactive Oxygen Species (ROS)SODLDHSuperoxide DismutaseapoptosisROSMDAischemic strokeHT22Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
LDH-IN-5
目录号：
HY-179027
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z