2. Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein
  3. Calcium Channel 5-HT Receptor
  4. Levemopamil

Levemopamil 是一种钙通道阻滞剂及 5-HT2 受体拮抗剂。Levemopamil 可对缺血性急性肾损伤发挥肾脏保护作用。Levemopamil 可用于缺血性急性肾衰竭的相关研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Levemopamil

Levemopamil Chemical Structure

CAS No. : 101238-51-1

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Levemopamil:

Levemopamil 相关抗体

Top Publications Citing Use of Products

查看 Calcium Channel 亚型特异性产品:

查看所有亚型
N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Levemopamil is a calcium channel blocker and 5-HT2 receptor antagonist. Levemopamil exerts renoprotective effects against ischemic acute kidney injury. Levemopamil is applicable to research related to ischemic acute renal failure[1].

体内研究
(In Vivo)

Levemopamil (6 mg/kg/h；静脉注射；持续输注 7 h) 可在大鼠少尿型缺血性急性肾损伤模型中短暂将少尿转变为非少尿，维持低水平肾小球滤过功能，并保护皮质线粒体 ATP 的合成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (female, adult, 191-239 g, left unilateral renal artery occlusion for 1 hour followed by 6 hours of reperfusion/reflow)[1]
Dosage: 6 mg/kg/h
Administration: i.v.; continuous infusion; from 1 hour before ischaemia until 6 hours after reflow
Result: Significantly increased urine flow and maintained measurable endogenous creatinine clearance in the ischaemic left kidney at 2 and 6 h of reperfusion.
Largely preserved mitochondrial ATP synthesis and normal ADP/O ratio.
Slightly attenuated the rise in cortical mitochondrial calcium content.
分子量

334.50

Formula

C23H30N2
CAS 号
中文名称

左依莫帕米
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Levemopamil 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Levemopamil101238-51-1左依莫帕米Calcium Channel5-HT ReceptorCa2+ channelsCa channelsSerotonin Receptor5-hydroxytryptamine Receptorrat kidneysischaemic acute renal failureischaemic kidneysconscious ratsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Levemopamil
目录号：
HY-113581
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z