2. Metabolic Enzyme/Protease
  3. ANGPTL
  4. Lexosiran sodium

Lexosiran sodium 是一种 siRNA，能够抑制 ANGPTL3（血管生成素相关蛋白 3）的合成，可用于抗高血脂的研究。

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RNA, ([1′-de(6-amino-9H-purin-9-yl)]A-(5′→5′)-sp-Gm-Am-Am-Um-Gm-Gm-Am-Am-(2′-deoxy-2′-fluoro)G-Gm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)A-Um-Am-Cm-Um-Cm-Um-Am-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), 3′-[O-[1-[18-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-6,10-bis[2-[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]-2-oxoethyl]-1,5,12-trioxo-16-oxa-6,10,13-triazaoctadec-1-yl]-4-piperidinyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)U-sp-Am-Gm-Am-Gm-(2′-deoxy-2′-fluoro)U-Am-Um-Am-Am-(2′-deoxy-2′-fluoro)C-Cm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-Cm-Am-Um-sp-Um-sp-Cm) (1:1) (sodium)

Lexosiran sodium Chemical Structure

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

Other Forms of Lexosiran sodium:

Lexosiran sodium 相关抗体

Top Publications Citing Use of Products

查看 ANGPTL 亚型特异性产品:

查看所有亚型
ANGPTL3 ANGPTL4 ANGPTL8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lexosiran sodium is a siRNA that inhibits ANGPTL3 angiopoietin-related protein 3 synthesis, and can be use for the study of antihyperlipidaemic.

IC50 & Target

ANGPTL3

 

分子量

15667.9 (free acid)

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lexosiran sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LexosiranANGPTLAngiopoietin-like proteinInhibitorinhibitorinhibit

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产品名称：
Lexosiran sodium
目录号：
HY-185318A
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