1. Vitamin D Related/Nuclear Receptor
  2. Orphan Nuclear Receptor
  3. LRH-1 antagonist-1 dihydrochloride

LRH-1 antagonist-1 (Compound 3d2) dihydrochloride 是一种 LRH-1 拮抗剂,其 Kd 为 1.8 μM。LRH-1 antagonist-1 dihydrochloride 抑制 LRH-1 转录活性,降低 G0S2 表达。LRH-1 antagonist-1 dihydrochloride 抑制 LRH-1 阳性癌细胞增殖。LRH-1 antagonist-1 dihydrochloride 可用于研究胰腺癌、结肠癌和乳腺癌。

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LRH-1 antagonist-1 dihydrochloride

LRH-1 antagonist-1 dihydrochloride Chemical Structure

CAS No. : 2932459-63-5

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  • 参考文献

生物活性

LRH-1 antagonist-1 (Compound 3d2) dihydrochloride is a LRH-1 antagonist with a Kd of 1.8 μM. LRH-1 antagonist-1 dihydrochloride inhibits the transcriptional activity of LRH-1 and reduces the expression of G0S2. LRH-1 antagonist-1 dihydrochloride inhibits the proliferation of LRH-1-positive cancer cells. LRH-1 antagonist-1 dihydrochloride can be used for research on pancreatic cancer, colon cancer and breast cancer[1].

分子量

437.41

Formula

C21H30Cl2N6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

LRH-1 antagonist-1 dihydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LRH-1 antagonist-1 dihydrochloride
目录号:
HY-128453A
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