1. 疾病领域
  2. 癌症
  3. LSPN925

LSPN925 是一种抗癌剂。LSPN925 对肿瘤细胞具有细胞毒性和抗增殖活性。LSPN925 具有预测的口服生物利用度,肝毒性和急性毒性风险低,且无心脏毒性风险。LSPN925 可用于卵巢癌、黑色素瘤、乳腺癌的研究。

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LSPN925

LSPN925 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LSPN925 is an anticancer agent. LSPN925 exhibits cytotoxic and antiproliferative activities against tumor cells. LSPN925 has predicted oral bioavailability, low risks of hepatotoxicity and acute toxicity, and no risk of cardiotoxicity. LSPN925 can be used for the research of ovarian cancer, melanoma and breast cancer[1].

体外研究
(In Vitro)

LSPN925 (48 h) 可抑制 A2780、A375 和 MCF-7 癌细胞的活力[1]
LSPN925 (48 h) 会改变 A2780 卵巢癌细胞的形态并降低其存活率,膜损伤增加和细胞密度降低的结果可证明这一点[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: A2780 ovarian cancer cells, A375 human melanoma cells, MCF-7 breast cancer cells, MRC-5 non-cancerous lung cells
Concentration: /
Incubation Time: 48 h
Result: Exhibited dose-dependent cytotoxicity against A2780, A375, and MCF-7 cancer cell lines, with IC50 values of 29.59 μM, 65.15 μM, and 81.20 μM, respectively.
Showed no significant cytotoxicity in non-cancerous MRC-5 cells (IC50 > 100 μM).
分子量

434.44

Formula

C24H22N2O6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

LSPN925 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LSPN925
目录号:
HY-182780
需求量: