2. GPCR/G Protein
  3. GPR84
  4. LY237

LY237 是一种 GPR84 (pEC50 = 10.15) 的高效完全激动剂。LY237 可以用于炎症和纤维化疾病的研究。

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LY237

LY237 Chemical Structure

CAS No. : 1892576-07-6

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规格 价格 是否有货 数量
5 mg ￥1710
In-stock
10 mg ￥2700
In-stock
25 mg ￥5400
In-stock
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LY237 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LY237 is a highly efficient complete agonist of GPR84 (pEC50 = 10.15). LY237 can be used for research on inflammation and fibrosis conditions[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
0.00018 μM
Compound: 51
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay
[PMID: 27326330]
HEK293 EC50
0.352 nM
Compound: 51
Agonist activity at GPR84 (unknown origin) expressed in in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 mins followed by forskolin addition measured after 30 mins by HTRF assay
Agonist activity at GPR84 (unknown origin) expressed in in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 mins followed by forskolin addition measured after 30 mins by HTRF assay
[PMID: 27326330]
分子量

237.34

Formula

C14H23NO2
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

LY237 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY2371892576-07-6LY 237LY-237GPR84G protein coupled receptor 84agonistinflammationfibrosisInhibitorinhibitorinhibit

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产品名称：
LY237
目录号：
HY-178234
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