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  3. Reference Standards mGluR
  4. LY2389575 hydrochloride (Standard)

LY2389575 hydrochloride (Standard) 是 LY2389575 (hydrochloride) (HY-107509) 的分析标准品。本产品用于研究及分析应用。LY2389575 hydrochloride 是一种选择性和非竞争性的 mGlu3 负变构调节剂 (NAM)，IC50 值为 190 nM。LY2389575 hydrochloride 能诱导 Mrc1 水平升高。LY2389575 hydrochloride 还能放大 β 淀粉样蛋白 (Aβ) 的毒性，可用于阿尔兹海默症的研究。

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LY2389575 hydrochloride (Standard)

LY2389575 hydrochloride (Standard) Chemical Structure

CAS No. : 885104-09-6

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LY2389575 hydrochloride (Standard) 相关抗体

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生物活性

LY2389575 hydrochloride (Standard) is the analytical standard of LY2389575 (hydrochloride) (HY-107509). This product is intended for research and analytical applications. LY2389575 hydrochloride is a selective and noncompetitive mGlu3 negative allosteric modulator (NAM), with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in Mrc1 levels. LY2389575 hydrochloride also independently amplifies Amyloid beta (Aβ) toxicity and can be used in study of Alzheimer's disease[1][2][3].

分子量

438.58

Formula

C15H16BrCl3N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LY2389575 hydrochloride (Standard) 相关分类

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Keywords:

LY2389575 hydrochloride (Standard)885104-09-6Reference StandardsmGluRMetabotropic glutamate receptorsAlzheimer's diseaseAβAmyloid betaInhibitorinhibitorinhibit

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