2. Academic Validation
  3. Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor

Synthesis and activity of a potent, specific azabicyclo[3.3.0]-octane-based DPP II inhibitor

  • Bioorg Med Chem Lett. 2007 Jan 15;17(2):507-10. doi: 10.1016/j.bmcl.2006.10.012.
Olga Danilova 1,  Bei Li,  A Katrin Szardenings,  Brigitte T Huber,  Jonathan S Rosenblum
Affiliations

Affiliation

  • 1 Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA.
PMID: 17055271 DOI: 10.1016/j.bmcl.2006.10.012
Abstract

A cell permeable DPP II [also known as DPP2, DPP7, and quiescent cell proline dipeptidase (QPP)] inhibitor has been synthesized. The azabicyclo[3.3.0]octane-based inhibitor is potent and selective and elicits very similar quiescent lymphocyte death to previously characterized inhibitors that are not as selective.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z