2. Academic Validation
  3. Aminopyrrolidineamide inhibitors of site-1 protease

Aminopyrrolidineamide inhibitors of site-1 protease

  • Bioorg Med Chem Lett. 2007 Aug 15;17(16):4411-4. doi: 10.1016/j.bmcl.2007.06.031.
Bruce A Hay 1,  Barbara Abrams,  Allice Y Zumbrunn,  James J Valentine,  Laurie C Warren,  Stephen F Petras,  Lorraine D Shelly,  Angela Xia,  Alison H Varghese,  Julie L Hawkins,  Jennifer A Van Camp,  Michael D Robbins,  Katherine Landschulz,  H James Harwood Jr
Affiliations

Affiliation

  • 1 Pfizer Global Research and Development-Groton Laboratories, Groton, CT 06340, USA. burce_hay@sbcglobal.net
PMID: 17583500 DOI: 10.1016/j.bmcl.2007.06.031
Abstract

The discovery and efficacy of a series of potent aminopyrrolidineamide-based inhibitors of sterol regulatory element binding protein site-1 protease is described.

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