2. Academic Validation
  3. Isolation of 2-pyridone alkaloids from a New Zealand marine-derived penicillium species

Isolation of 2-pyridone alkaloids from a New Zealand marine-derived penicillium species

  • J Nat Prod. 2009 Mar 27;72(3):477-9. doi: 10.1021/np800627f.
E Dilip de Silva 1,  Anna-Skrollan Geiermann,  Maya I Mitova,  Philipp Kuegler,  John W Blunt,  Anthony L J Cole,  Murray H G Munro
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Colombo, P.O. Box 1490, Colombo 3, Sri Lanka.
PMID: 19323568 DOI: 10.1021/np800627f
Abstract

Fermentation of a Penicillium sp. isolated from a surface-sterilized thallus segment of the brown alga Xiphophora gladiata, collected from Macrocarpa Point, Otago, New Zealand, in half-strength potato dextrose broth led to the isolation and characterization of three alkaloids: the known N-hydroxy-2-pyridone, PF1140 (1), and two new 2-pyridones, 2 and 3.

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