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  3. Three new diterpenoid alkaloids from the roots of Aconitum duclouxii

Three new diterpenoid alkaloids from the roots of Aconitum duclouxii

  • J Asian Nat Prod Res. 2014;16(4):345-50. doi: 10.1080/10286020.2014.881802.
Tian-Peng Yin 1,  Le Cai,  Jian-Min He,  Jian-Wei Dong,  Hai-Xian Fang,  Hao Zhou,  Zhong-Tao Ding
Affiliations

Affiliation

  • 1 a Key Laboratory of Medicinal Chemistry for Nature Resource , Ministry of Education, School of Chemical Science and Technology, Yunnan University , Kunming 650091 , China.
PMID: 24498916 DOI: 10.1080/10286020.2014.881802
Abstract

Three new C₁₉-diterpenoid Alkaloids, ducloudines C (1), D (2), and E (3), were isolated from the roots of Aconitum duclouxii. Their structures were established on the basis of extensive spectroscopic analyses. Ducloudine C (1) is the first aconitine-type C₁₉-diterpenoid alkaloid with a C=O group at C-3 and a C=C bond between C-1 and C-2. All compounds were tested for their biological activities against one pathogenic fungi and two pathogenic bacteria.

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