2. Academic Validation
  3. Binding characteristics of 3H-prazosin to rat brain alpha-adrenergic receptors

Binding characteristics of 3H-prazosin to rat brain alpha-adrenergic receptors

  • Eur J Pharmacol. 1979 May 1;55(3):323-6. doi: 10.1016/0014-2999(79)90202-4.
P Greengrass,  R Bremner
PMID: 37098 DOI: 10.1016/0014-2999(79)90202-4
Abstract

3H-Prazosin binding to membranes from rat brain is saturable, Bmax, 77 fmol/mg protein, of high affinity, KD, 0.28 nM and with a drug specificity indicating that it labels alpha-adrenergic receptors. The ranking of alpha-antagonists for these binding sites suggests that 3H-prazosin may be useful in identifying a subpopulation of alpha-receptors (alpha1) in the central nervous system.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z