Soluble CSF1R alleviates microgliopathy in a CSF1R-related leukoencephalopathy (CRL) mouse model

Affiliations

• 1 Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China.
• 2 Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China.
• 3 Division of Life Science and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
• 4 Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. hszhang@cqmu.edu.cn.
• 5 Department of Neurobiology, School of Basic Medical Sciences, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, 400016, China. hszhang@cqmu.edu.cn.
• 6 Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. yunzhang@xmu.edu.cn.
• 7 Xiamen Key Laboratory of Brain Center, The First Affiliated Hospital of Xiamen University, Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. honghua@xmu.edu.cn.
• 8 Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. honghua@xmu.edu.cn.