1. Academic Validation
  2. Tirzepatide improves neutrophilic inflammation in obese asthmatic mice by downregulating Th17 cell differentiation

Tirzepatide improves neutrophilic inflammation in obese asthmatic mice by downregulating Th17 cell differentiation

  • Mol Biol Rep. 2025 Dec 13;53(1):197. doi: 10.1007/s11033-025-11366-6.
Lu Sun # 1 Su-Yan Yao # 2 Zhong-Fu Zuo 3 4 Sheng-Xue Yu 3 4 Hong-Dan Yu 3 4 Qing-Lin Sun 5 Han-Song Zheng 6 Yang Hou 3 Si-Jing Lu 7 Tie-Feng Yao 8 9
Affiliations

Affiliations

  • 1 Department of Pathology, Jinzhou Medical University, Jinzhou, China.
  • 2 Department of pathophysiology, Jinzhou Medical University, Jinzhou, China.
  • 3 Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, China.
  • 4 Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou, China.
  • 5 Department of Third Clinical College, Jinzhou Medical University, Jinzhou, China.
  • 6 Department of First Clinical College, Tianjin Medical University, Tianjin, China.
  • 7 The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China. yusilou@126.com.
  • 8 Department of Anatomy, Histology and Embryology, Jinzhou Medical University, Jinzhou, China. yaotf@jzmu.edu.cn.
  • 9 Liaoning Key Laboratory of Diabetic Cognitive and Perceptive Dysfunction, Jinzhou Medical University, Jinzhou, China. yaotf@jzmu.edu.cn.
  • # Contributed equally.
Keywords

Obesity-related asthma · Th17 · Tirzepatide · NOTCH · Neutrophil.

Figures
Products
Inhibitors & Agonists
Other Products