2. Academic Validation
  3. An antifungal bibenzyl from the New Zealand liverwort, Plagiochila stephensoniana. Bioactivity-directed isolation, synthesis, and analysis

An antifungal bibenzyl from the New Zealand liverwort, Plagiochila stephensoniana. Bioactivity-directed isolation, synthesis, and analysis

  • J Nat Prod. 1993 Sep;56(9):1444-50. doi: 10.1021/np50099a002.
S D Lorimer 1,  N B Perry,  R S Tangney
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Otago, Dunedin, New Zealand.
PMID: 8254344 DOI: 10.1021/np50099a002
Abstract

The bioactivity-directed isolation of 4-hydroxy-3'-methoxybibenzyl [1] from a New Zealand liverwort, Plagiochila stephensoniana, is described. Compound 1 exhibited Antifungal and Antibacterial activity. Compound 1 is not considered to be a useful taxonomic marker. Syntheses of 1, Stilbenes 2 and 3, and some derivatives were made and the biological activities were compared.

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