2. Academic Validation
  3. Anthraquinones, naphthohydroquinones and naphthohydroquinone dimers from Rubia cordifolia and their cytotoxic activity

Anthraquinones, naphthohydroquinones and naphthohydroquinone dimers from Rubia cordifolia and their cytotoxic activity

  • Chem Pharm Bull (Tokyo). 1993 Oct;41(10):1869-72. doi: 10.1248/cpb.41.1869.
H Itokawa 1,  Z Z Ibraheim,  Y F Qiao,  K Takeya
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, Tokyo College of Pharmacy, Japan.
PMID: 8281583 DOI: 10.1248/cpb.41.1869
Abstract

Further investigation of the roots of Rubia cordifolia resulted in the isolation of four new naphthohydroquinones and two naphthohydroquinone dimers, and one known naphthohydroquinone, one naphthoquinone, two Anthraquinones and one naphthohydroquinone dimer. The structures of these compounds were established by various chemical and spectroscopic methods including two dimensional NMR techniques. Also, the isolated compounds were submitted to a bio-assay for cytotoxic and antitumor activity.

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