2. Epigenetics
  3. Epigenetic Reader Domain
  4. Menin-MLL-IN-32

Menin-MLL-IN-32 (compound 51) 是一种 Menin-MLL 相互作用抑制剂，在 HTRF 检测中，其 IC50 为 0.042 nM。Menin-MLL-IN-32 抑制 MEIS1 mRNA 的表达，其 IC50 为 11 nM。Menin-MLL-IN-32 显示出抗增殖作用，对 MOLM14 细胞、OCI-AML3 细胞和 KO-52 细胞的 IC50 值分别为 8 nM、24 nM 和 1900 nM。Menin-MLL-IN-32 可用于白血病的研究。

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Menin-MLL-IN-32

Menin-MLL-IN-32 Chemical Structure

CAS No. : 2879330-24-0

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Menin-MLL-IN-32 相关抗体

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  • 生物活性

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生物活性

Menin-MLL-IN-32 (compound 51) is a Menin-MLL interaction inhibitor with an IC50 of 0.042 nM in HTRF assay. Menin-MLL-IN-32 inhibits MEIS1 mRNA expression with an IC50 of 11 nM. Menin-MLL-IN-32 shows anti-proliferative effects, with IC50 values of 8 nM, 24 nM and 1900 nM for MOLM14 cells, OCI-AML3 cells and KO-52 cells, respectively. Menin-MLL-IN-32 can be used for the study of leukemia[1].

分子量

547.71

Formula

C32H42FN5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Menin-MLL-IN-32 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Menin-MLL-IN-322879330-24-0Epigenetic Reader DomainMenin-MLL Interaction InhibitorleukemiaMEIS1 mRNA expressionInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-160733
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