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  3. Metallibure

Metallibure (ICI 33828) 是一种二硫代氨基甲酰肼衍生物和促性腺功能阻断剂。Metallibure 可阻断硬骨鱼垂体促性腺激素作用,抑制生殖细胞成熟。Metallibure 不会影响甲状腺组织学结构,但会使甲状腺上皮细胞核体积缩小。Metallibure 可用于内分泌疾病的研究。

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Metallibure

Metallibure Chemical Structure

CAS No. : 926-93-2

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  • 生物活性

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生物活性

Methallibure (ICI 33828) is a dithiocarbamoylhydrazine derivative and gonadotropic function blocker. Methallibure can block the action of pituitary gonadotropins in teleost fishes and inhibit germ cell maturation. Methallibure does not affect the histological structure of the thyroid gland but reduces the nuclear volume of thyroid epithelial cells. Methallibure can be used in the research of endocrine diseases[1][2].

分子量

218.34

Formula

C7H14N4S2

CAS 号
性状

固体

颜色

White to off-white

中文名称

美他硫脲

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Metallibure
目录号:
HY-105636
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