2. Metabolic Enzyme/Protease
  3. Herbicide Acetyl-CoA Carboxylase
  4. Metamifop

Metamifop 是一种苗后脂类合成抑制剂除草剂，对稗草 (Echinochloa crus-galli) 叶绿体乙酰辅酶 A 羧化酶 (ACCase) 的羧基转移酶 (CT) 结构域的 IC50 为 41.1 nM。Metamifop 可抑制 CT 结构域的活性，从而阻断脂肪酸的生物合成。

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Metamifop

Metamifop Chemical Structure

CAS No. : 256412-89-2

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规格 价格 是否有货 数量
100 mg ￥1800
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1 g ￥5220
In-stock
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Metamifop 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Metamifop is a post-emergence lipid synthesis inhibitor herbicide, with an IC50 of 41.1 nM against the carboxyltransferase (CT) domain of chloroplast acetyl-CoA carboxylase (ACCase) in barnyard grass (Echinochloa crus-galli). Metamifop inhibits the activity of the CT domain, thereby blocking fatty acid biosynthesis[1].

体外研究
(In Vitro)

Metamifop 可强效抑制稗草 (Echinochloa crus-galli)中的乙酰辅酶 A 羧化酶 (ACCase) 活性，其 IC50 为 41.1 nM[1]。
Metamifop (3 ns) 通过 π-π 相互作用和依赖质子化的氢键结合于稗草 (Echinochloa crus-galli) CT 结构域的二聚体界面活性位点；与其他 ACCase 抑制剂相比，其结合区域具有独特性，且在 MD 模拟过程中结合位点会发生构象变化[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Metamifop 相关抗体:
体内研究
(In Vivo)

Metamifop (12.5-90 g a.i. ha−1; foliar spray) 可剂量依赖性地破坏敏感型稗草 (Echinochloa crus-galli) 植株的叶绿体超微结构，改变其生长早期 CT 结构域的基因表达，并能高效抑制 ACCase 活性 (IC50 = 41.1 nM)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

440.86

Formula

C23H18ClFN2O4
CAS 号
性状

固体

中文名称

恶唑酰草胺
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Metamifop 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metamifop256412-89-2恶唑酰草胺HerbicideAcetyl-CoA CarboxylaseACC, Acetyl Coenzyme A Carboxylasechloroplastic acetyl-coenzyme A carboxylase (ACCase)Gly171chloroplastEchinochloa crus-gallifatty acid biosynthesisTyr175carboxyltransferase (CT) domainPhe391'Thr194Lys201Inhibitorinhibitorinhibit

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