2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Potassium Channel Endogenous Metabolite
  4. Minoxidil hydrochloride

Minoxidil hydrochloride  (Synonyms: U10858 hydrochloride)

目录号: HY-B0112A
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Minoxidil (U10858) hydrochloride 是一种是 ATP 敏感的钾通道 (KATP) 开放剂，是有效的口服降压剂和外周血管舒张剂，可促进血管扩张并促进头发的生长。Minoxidil hydrochloride 还是一种大豆脂氧合酶的有效抑制剂，其 IC50 值为 20 μM。

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CAS No. : 69935-18-8

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Minoxidil hydrochloride 的其他形式现货产品:

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Minoxidil hydrochloride 相关抗体

Top Publications Citing Use of Products

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: Bioact Mater. 2025 Nov 14:57:344-357.  [Abstract]

    Cell proliferation assay in DPCs and HFSCs treated with DHT (500 μM) and DHT combined with Minoxidil (20 μM), tFNFs (0.25 μM), Que (20 μM), and TQC (tFNFs/Que: 0.25/20 μM) for 24 h.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: Bioact Mater. 2025 Nov 14:57:344-357.  [Abstract]

    Time-course observations of hair growth of samples at 1, 4, 7, 10, 14, 15, 18, 21, 24, and 28 days (n = 5). The results showed that Minoxidil (5%; topical application, 100 μL per application) treatment, serving as a positive control, led to gradual hair regrowth starting from day 10, with marked hair coverage observed by day 28.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5.  [Abstract]

    Minoxidil (0.5 mM； 48 h) led to a significant increase in the expression of epithelial differentiation markers in 786-O sccRCC cells.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5.  [Abstract]

    Minoxidil (0.25-0.5 mM; 48 h) did not cause substantial 786-O ccRCC cell death.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5.  [Abstract]

    Minoxidil (6 mg/kg; gavage) significantly reduced the Ki-67 index in sccRCC xenograft mouse models.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: J Adv Res. 2025 Oct 16:S2090-1232(25)00818-5.  [Abstract]

    Minoxidil (6 mg/kg; gavage) significantly reduced the tumor growth rate in sccRCC xenograft mouse models.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8.  [Abstract]

    Representative bright-field images of ARPKD (ARPKD Epi-17) kidney organoids treated with a concentration gradient of ST034307 and Minoxidil (0.1-5 μM) in the presence of FSK for 3 days. Scale bars, 200 μm.

    Minoxidil hydrochloride purchased from MCE. Usage Cited in: Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8.  [Abstract]

    Minoxidil (i.p.; once daily for 3 weeks) administered at 1 and 5 mg/kg/day reduced the calculated cystic index of ARPKD kidney organoid xenografts from host NSG mice by 18.85% and 33.93%, respectively.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Minoxidil (U10858) hydrochloride is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil hydrochloride is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3].

    分子量

    245.71

    Formula

    C9H16ClN5O
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Minoxidil hydrochloride 相关分类

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    • 稀释计算器

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    The dilution calculator equation

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Minoxidil69935-18-8U10858U 10858U-10858Potassium ChannelEndogenous MetaboliteKcsAInhibitorinhibitorinhibit

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