1. Metabolic Enzyme/Protease
  2. Herbicide Phosphatase β-glucuronidase
  3. Morfamquat (dichloride)

Morfamquat dichloride (PP 745) 是一种联吡啶类除草剂。Morfamquat dichloride 急性中毒后强烈刺激网状内皮系统,并导致溶酶体膜损伤和酶泄漏,同时对肝细胞高尔基体功能及相关的糖代谢途径产生干扰。Morfamquat dichloride 显著升高酸性磷酸酶 (acid phosphatase) 和 β-葡糖醛酸酶 (β-glucuronidase) 的活性,对小鼠产生毒性作用,而预先给予维生素 E 可缓解其毒性。

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Morfamquat (dichloride)

Morfamquat (dichloride) Chemical Structure

CAS No. : 4636-83-3

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  • 生物活性

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生物活性

Morfamquat dichloride (PP 745) is a bipyridine herbicide. Acute poisoning by Morfamquat dichloride strongly stimulates the reticuloendothelial system, causes lysosomal membrane damage and enzyme leakage, and interferes with the function of hepatocyte Golgi apparatus and related glucose metabolic pathways. Morfamquat dichloride significantly increases the activities of acid phosphatase and β-glucuronidase, exerting toxic effects on mice, while pre-administration of vitamin E alleviates such toxicity[1].

分子量

539.49

Formula

C26H36Cl2N4O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Morfamquat (dichloride)
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